BIOCHEMICAL STUDIES ON SOME NANOTECHNOLOGY APPLICATIONS

Document Type : original papers

Authors

1 Prof. of Agric Biochemistry, Fac. of Agric., Menoufia Univ.

2 Prof. of Textile Chemistry and Technology, National Research Center, Dokki, Cairo.

3 Associate prof. of Agric Biochemistry, Fac. of Agric., Menoufia Univ.

Abstract

Recent advances in nanoscience and nanotechnology radically changed the way we diagnose, treat, and prevent various diseases in all aspects of human life. Silver nanoparticles (AgNPs) are one of the most vital and fascinating nanomaterials among several metallic nanoparticles that are involved in biomedical applications.             our study aims to introduce a simple, rapid and economical route to synthesize silver nanoparticles (AgNPs) using aqueous and methanolic extracts from two medicinal plants; ginger and lemon grass as reducing and stabilizing agent, AgNPs synthesis was inferred by the change of color from yellow to brown. The size, morphology and stability of AgNPs depend on the active ingredients in the extracts. AgNPs size and morphology were characterized using Ultraviolet-visible (UV-Vis) spectrum of synthesized AgNPs shows a peak from 410-425 nm approximately. and transmission electron microscopy (TEM) analysis indicated spherical shape of nanoparticles with average size of 13.0 - 35 nm. We investigate the antioxidant effect of (AgNPs) synthesized from aqueous and methanolic extracts in both in vitro and in vivo, and we can conclude that, silver nanoparticles recorded the most potent in vitro  and in vivo antioxidant effect and can   protect liver, kidney and heart of rats against oxidative stress caused by H2O2 (0.5 % in drinking water), also have antibacterial effect against some human pathogenic bacteria.

Keywords

Menoufia Journal of Agricultural Biotechnology
Volume 5, Issue 1 - Serial Number 1
January and February 2020
Pages 41-42

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