BIOCHEMICAL AND BIOLOGICAL STUDIES ON ZINC OXIDE NANOPARTICLES

Hamam, Mostafa; Mohamed, Samir; Mansour, Salah; Rashed, Reda

doi:10.21608/mjab.2024.258618.1015

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Menoufia Journal of Agricultural Biotechnology

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	BIOCHEMICAL AND BIOLOGICAL STUDIES ON ZINC OXIDE NANOPARTICLES
Article 3, Volume 9, Issue 1, January 2024, Page 1-10 PDF (727.33 K)
Document Type: original papers
DOI: 10.21608/mjab.2024.258618.1015
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Authors
mostafa hamam¹; samir mohamed²; salah mansour²; reda rashed ²
¹Faculty Agricultural-Biochemistry Dep .-Mynofia University
²Biochemistry Department, Faculty of Agriculture, Menofia University, Shibin El-Kom, Egypt
Abstract
The current study endeavors to examine the synthesis of zinc oxide nanoparticles, which find utility in various domains such as biomedical, electrochemistry, and catalysis. The zinc oxide nanoparticles were fabricated through sol gel techniques utilizing zinc acetate and zinc sulfate as precursors. Subsequently, these nanoparticles were subjected to characterization using X-ray diffraction, FTIR analysis, and TEM analysis. Furthermore, the antioxidant activity of the zinc oxide nanoparticles was evaluated employing the DPPH assay, while their antimicrobial efficacy against Gram positive and Gram negative bacteria was also investigated. Additionally, the toxicity of the zinc oxide nanoparticles on adult male Westar rats was assessed by assessing liver function, kidney function, lipid profile, and blood sugar level. The outcomes of the study revealed a significant rise in all liver and kidney functions, glucose, cholesterol, low-density cholesterol, and triglycerides, in comparison to the negative control. However, the high-density cholesterol exhibited a decrease relative to the negative control
Keywords
Zinc oxide nanoparticles; toxicity; antimicrobial; antioxidant
Main Subjects
Agricultural Biotechnology and related articles researches


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